Newton's Second Law of Motion Is Represented by ____ $E = m _ { 0 } c ^ { 2 }$

Newton's second law of motion is represented by ____.

A) $E = m _ { 0 } c ^ { 2 }$
B) $F = - \frac { G M m } { r ^ { 2 } }$
C) $V _ { c } = \sqrt { \frac { G M } { r } }$
D) $V _ { c } = \sqrt { \frac { 2 G M } { r } }$
E) $F = m a$