____ affects virtually all tissues in the body, and therefore may have a variety of effects, with the most common manifestation is joint pain and swelling, which affects approximately 95% of patients.

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Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect virtually all tissues in the body, leading to a wide range of symptoms, with joint pain and swelling being common manifestations in about 95% of patients.

____ Affects Virtually All Tissues in the Body, and Therefore