Read the paragraph below and answer the questions that follow.
(1) Some seemingly harmless substances can interfere with the way medicines work inside the body. (2) Take grapefruit juice, for example. (3) It disrupts the action of enzymes that break down drugs in the small intestine before they are absorbed into the bloodstream. (4) Therefore, taking a medication with grapefruit juice may cause the drug to enter the blood in dangerously high concentrations. (5) If this happens, not only is the drug less effective, but serious side effects can result. (6) Many common medications, including antidepressants, antihistamines, and cholesterol drugs, are negatively affected by grapefruit juice.
Select the number of the topic sentence in the paragraph above.
A) Sentence 1
B) Sentence 2
C) Sentence 6

Question

Quizplus · Accepted Answer

The topic sentence is the sentence that introduces the main idea of the paragraph. In this case, sentence 1 introduces the idea that some seemingly harmless substances can interfere with the way medicines work inside the body. Therefore, sentence 1 is the topic sentence of the paragraph. Sentence 2, on the other hand, is an example of a substance that can interfere with medicines. Sentence 6 is a supporting detail that provides more information about the types of medications that are affected by grapefruit juice.

Read the Paragraph Below and Answer the Questions That Follow