A mature megakaryocyte can release as many as 3000 platelets into the blood.

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A mature megakaryocyte can release as many as 3000 platelets into the blood. This is because megakaryocytes undergo endomitosis, a process in which they replicate their DNA multiple times without cell division, resulting in a large cell with multiple nuclei. These nuclei can each produce platelets, leading to the release of thousands of platelets by a single megakaryocyte.

A Mature Megakaryocyte Can Release as Many as 3000 Platelets