What effect on the treatment of secondary hypertension would you expect from angiotensin-converting enzyme (ACE)inhibitor drugs?
A) When secondary hypertension occurs, the cells of the juxtaglomerular apparatus secrete renin, which in turn results in angiotensin production and increased blood pressure, so giving ACE inhibitors may reduce the production of angiotensin and lower the blood pressure.
B) Secondary hypertension is caused by stenosis of the renal artery, so ACE inhibitors will relax the vessel, thus reducing blood pressure.
C) Secondary hypertension is caused by stenosis of the renal artery, so ACE inhibitors will decrease atherosclerotic plaque and result in a lower blood pressure.
D) ACE inhibitors will not have any effect on secondary hypertension.

Question

What effect on the treatment of secondary hypertension would you expect from angiotensin-converting enzyme (ACE)inhibitor drugs?
A) When secondary hypertension occurs, the cells of the juxtaglomerular apparatus secrete renin, which in turn results in angiotensin production and increased blood pressure, so giving ACE inhibitors may reduce the production of angiotensin and lower the blood pressure.
B) Secondary hypertension is caused by stenosis of the renal artery, so ACE inhibitors will relax the vessel, thus reducing blood pressure.
C) Secondary hypertension is caused by stenosis of the renal artery, so ACE inhibitors will decrease atherosclerotic plaque and result in a lower blood pressure.
D) ACE inhibitors will not have any effect on secondary hypertension.

Quizplus · Accepted Answer

ACE inhibitors work by blocking the conversion of angiotensin I to angiotensin II, leading to decreased vasoconstriction and decreased aldosterone secretion, resulting in lower blood pressure. In secondary hypertension, the underlying cause (such as renal artery stenosis) triggers the renin-angiotensin system, leading to increased angiotensin II and increased blood pressure. Thus, ACE inhibitors can be effective in treating secondary hypertension by reducing the production of angiotensin II and lowering blood pressure. Choices B and C are incorrect as they describe a different cause of hypertension and mechanism of action of ACE inhibitors. Choice D is incorrect as ACE inhibitors have been shown to be effective in treating secondary hypertension.

What Effect on the Treatment of Secondary Hypertension Would You