The impulse of the United States of America to isolate itself from world affairs, for example, rejecting membership in the League of Nations, was a response to _____.

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The impulse to isolate oneself from world affairs was a response to eighteenth-century power politics and repetitive wars in Europe, which had a strong influence on American foreign policy at the time. The rejection of membership in the League of Nations was seen as a way to avoid becoming entangled in international conflicts and to focus on domestic issues. It was not directly related to the Great Patriotic War in Russia, growing globalization, or interventionism.

The Impulse of the United States of America to Isolate