Which of the following antigen-specific immune cells produce cytokines, which facilitate various immune reactions?

Question

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Helper T-cells produce cytokines, which facilitate the actions of B-cells and Cytotoxic T-cell.
B-cells are responsible for producing immunoglobulins or antibodies while cytotoxic cells directly attack and destroy pathogens.
Helper T-cells, cytotoxic cells and B-cells are all antigen-specific immune cells.
Macrophage cells are part of non-specific innate immune system which engulf and destroy bacteria and cellular debris during infection and injury.

Which of the Following Antigen-Specific Immune Cells Produce Cytokines, Which