A penicillin derivative is used to treat infections with an adult 24-hour dosage of 35 mg/kg of body mass. This is to be given in three injections daily. This antibiotic is prepared by the pharmacy in solution form with a concentration of 130 mg/5mL. What volume in milliliters should be given in each injection to an adult with a mass of 12.5kg?

Question

Quizplus · Accepted Answer

First, calculate the total daily dosage for an adult with a mass of 12.5 kg: 35 mg/kg * 12.5 kg = 437.5 mg/day. Since this dosage is divided into three injections, each injection will be 437.5 mg / 3 = 145.83 mg. To find the volume for each injection using the concentration 130 mg/5 mL, set up a proportion: 130 mg / 5 mL = 145.83 mg / x mL. Solving for x gives x = (145.83 mg * 5 mL) / 130 mg = 5.6 mL.

A Penicillin Derivative Is Used to Treat Infections with an Adult