A client with hypertension is prescribed lisinopril. The nurse instructs the client to notify the health care provider immediately if which adverse effect occurs when taking this medication?

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11ecbb05_cc6a_9398_b433_95c228b205a6_MD0009_00 Lisinopril (Prinivil, Zestril) is an angiotensin-converting enzyme (ACE) inhibitor prescribed to treat hypertension and slow the progression of heart failure. Lisinopril has a low incidence of serious adverse effects except angioedema (rapid swelling of lips, tongue, throat, face, and larynx). Angioedema can lead to airway obstruction and possible death. ACE inhibitors are the most frequent medications causing drug-induced angioedema. The risk is 5 times greater for African Americans than for Caucasians. If clients experience symptoms of angioedema, they are instructed to discontinue the drug and notify the HCP immediately. (Options A and B) Persistent, dry cough is a common (5%-20%), annoying adverse effect of ACE inhibitors that is caused by a buildup of bradykinin in the lung. If the client cannot tolerate this side effect, the HCP can prescribe an angiotensin-receptor blocker instead, which has a similar action. Other common adverse effects of ACE inhibitors include orthostatic hypotension (dizziness) and hyperkalemia. (Option C) Rapid-onset confusion is not an adverse effect associated with lisinopril. Educational objective: ACE inhibitors (eg, captopril, enalapril, lisinopril, ramipril) have a low incidence of serious adverse effects except angioedema (rapid swelling of lips, tongue, throat, face, and larynx). More common adverse effects of ACE inhibitors include dry cough, orthostatic hypotension, and hyperkalemia.

A Client with Hypertension Is Prescribed Lisinopril