What are some of the steps in eukaryotic transcriptional control?
A) A transcriptional repressor recruits nucleosome remodeling proteins that alter nucelosome positioning, modification, and composition. This allows for the formation of a closed chromatin complex, and binding of general transcription factors and RNA polymerase II. Histone cores remain on the gene as transcript elongation occurs.
B) A transcriptional repressor recruits general transcription factors and RNA polymerase II without affecting nucleosome positioning.
C) A transcriptional activator recruits nucleosome remodeling proteins that alter nucleosome positioning, modification and composition. This allows for the formation of an open chromatin complex, and binding of general transcription factors and RNA polymerase II. Finally as transcription elongation occurs, histone cores are evicted from the DNA to allow the RNA polymerase to transcribe the gene.
D) A transcriptional activator recruits general transcription factors and RNA polymerase II. Finally as transcription elongation occurs, histone cores remain with the DNA.
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