Pathological alterations that can occur during embryonic kidney development are being investigated by researchers at a national foundation for prematurity and birth abnormalities. Their study focuses on the inductive signals that are exchanged between the metanephric diverticulum and metanephric blastema, which promote their development into tissues that compose the adult kidney. Which of the following adult derivatives will fail to develop if a toxic insult occurs during early fetal development that preferentially inhibits the renal structures generated by the metanephric blastema?

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Eductional Objective: The glomeruli, Bowman's space, proximal tubules, the loop of Henle, and distal convoluted tubules are all formed by the metanephros (metanephric blastema). The ureteric bud develops into the kidney's collecting system, which includes the collecting tubules and ducts, major and minor calyces, renal pelvis, and ureters.

Pathological Alterations That Can Occur During Embryonic Kidney Development Are