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A 26-Year-Old Woman Comes to the Office for Follow-Up

Question 3

Multiple Choice

A 26-year-old woman comes to the office for follow-up.  The patient and her husband want to have a child, and she inquires about the risk of certain genetic conditions, including cystic fibrosis (CF) .  The patient is from a small city with a stable Caucasian population, where the carrier frequency for CF is 1/30 Caucasian individuals.  Her husband is from a nearby community, where CF carrier frequency in individuals of Asian descent is 1/100.  Both the patient, who is Caucasian, and her husband, who is of Asian descent, are healthy.  What is the probability that a child born to a mother from the Caucasian community and a father from the Asian community will have the disease?


A) 1/900
B) 1/1,000
C) 1/3,000
D) 1/6,000
E) 1/12,000

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