A 23-year-old asymptomatic male participates in clinical research and is found to be homozygous for the apolipoprotein E-4 allele. In the future, this patient is most likely to suffer from which of the following?

Question

A 23-year-old asymptomatic male participates in clinical research and is found to be homozygous for the apolipoprotein E-4 allele.  In the future, this patient is most likely to suffer from which of the following?

Quizplus · Accepted Answer

Eductional Objective: Early-onset familial Alzheimer disease is associated with three gene mutations: APP (chromosome 21), presenilin 1 and presenilin 2.  Late-onset familial Alzheimer disease is associated with apolipoprotein E4 genotype.

A 23-Year-Old Asymptomatic Male Participates in Clinical Research and Is