A young couple has successfully undergone in vitro fertilization. The father has cystic fibrosis, and the mother has a sibling who also has the disease. Both the father and the mother's sister have F508 mutations, but the mother's carrier status is unclear. Before deciding to have a child, the couple received thorough genetic counseling on the dangers of having a kid with cystic fibrosis. The unborn kid is indicated by the red arrow in the family tree below. What is the probability that the unborn child will have cystic fibrosis?

Question

A young couple has successfully undergone in vitro fertilization. The father has cystic fibrosis, and the mother has a sibling who also has the disease. Both the father and the mother's sister have F508 mutations, but the mother's carrier status is unclear. Before deciding to have a child, the couple received thorough genetic counseling on the dangers of having a kid with cystic fibrosis. The unborn kid is indicated by the red arrow in the family tree below.  What is the probability that the unborn child will have cystic fibrosis?

Quizplus · Accepted Answer

Eductional Objective: Based on the maternal and paternal pedigrees, the likelihood that an autosomal recessive illness would be transferred to a child may be determined. An unaffected person (with unaffected parents) who has a sibling with an autosomal recessive disorder has a two-thirds probability of being a carrier for that ailment.

A Young Couple Has Successfully Undergone in Vitro Fertilization