A 4-year-old kid is brought to the clinic for her yearly checkup. She has no chronic medical issues and has had all previously advised vaccines. Today, the patient will receive multiple immunizations, including a second measles vaccine. Which of the following IgM and IgG trends are likely to develop following initial and subsequent measles vaccinations?

Question

Quizplus · Accepted Answer

Eductional Objective: Short-lived plasma cells provide an early IgM response, which is followed by a delayed-onset, longer-lasting IgG response caused by T-cell dependent class switching (IgM peaks before IgG). Secondary reactions (e.g., booster vaccination, pathogen exposure) are characterized by a quick and persistent IgG response with a short-term, more muted IgM response due to the development of memory B cells.

A 4-Year-Old Kid Is Brought to the Clinic for Her