A 10-Day-Old Male Newborn Is Brought to the Emergency Department

A 10-day-old male newborn is brought to the emergency department by his mother because of episodes of weakness and spasms for the past 12 hours. His mother states that he has also had difficulty feeding and opening his mouth. He has not had fever, cough, diarrhea, or vomiting. He was born at 39 weeks' gestation via uncomplicated vaginal delivery at home. Pregnancy was uncomplicated. The mother refused prenatal vaccines out of concern they would cause side effects. She is worried his symptoms may be from some raw honey his older sister maybe inadvertently fed him 5 days ago. He appears irritable. His temperature is 37.1°C (98.8°F) . Physical examination shows increased muscle tone throughout, arching of the back, and dorsiflexed feet. In addition to avoid honey feeding to newborn, which of the following is the most effective strategy to prevent this condition?

A) Early postpartum breastfeeding
B) Prophylactic antibiotics
C) Prophylactic immune globulin
D) Vaccination of infants at birth
E) Vaccination of pregnant women