A 3-Year-Old Boy Is Brought to the Emergency Department Because

A 3-year-old boy is brought to the emergency department because of fever, vomiting, and diarrhea for 3 days. Her parents report at least 8 watery stools daily. She has had three upper respiratory tract infections since she started daycare 2 months ago but has otherwise been developing normally. Her mother has a history of celiac disease. The patient is at the 57th percentile for height and the 65th percentile for weight. Her immunizations are incomplete. Her temperature is 38.5°C (101.3°F) , pulse is 145/min, and blood pressure is 92/54 mm Hg. Examination shows dry mucous membranes and decreased skin turgor. Bowel sounds are hyperactive. Polymerase chain reaction testing of the stool sample yields a virus with a segmented, double-stranded RNA genome.  Which of the following pathologic findings is most likely to be present in this patient?

A) Blunting of the villi in the duodenum and proximal jejunum
B) Extensive colonic mucosal injury with yellow-white adherent layer
C) Flask-shaped ulcerations in the cecum and ascending colon
D) Foamy macrophages in the small intestinal lamina propria
E) Inflammatory infiltration and necrosis of the Peyer patches