Two Days After Hospital Admission and Surgical Treatment for a Cut

Two days after hospital admission and surgical treatment for a cut on his right thigh from a sickle, a 35-year-old man presents to the emergency department with wound swelling, fever, chills, and severe pain. He had a similar injury 4 months ago that resolved after treatment with bacitracin ointment and daily dressings. He works on a farm on the outskirts of the city. He appears anxious. His temperature is 38.5°C (101.3°F) , pulse is 103/min, and blood pressure is 114/76 mm Hg. Examination shows a 6-cm edematous deep, foul-smelling wound on the medial surface of the right thigh. The skin over the thigh appears darker than the skin on the lower leg. There are multiple blisters around the wound. Light palpation around the wound causes severe pain; crepitus is present. The microorganism most likely responsible for this patient's condition is also commonly associated with which of the following conditions?

A) Heart murmur and valve abscess
B) Persistent cough and pharyngeal exudates
C) Relentless headaches and nausea
D) Transient watery diarrhea and abdominal discomfort
E) Urinary frequency and burning