A 26-year-old man is being screened as a potential kidney donor for his mother, who has end-stage renal disease. The patient has no history of diabetes, hypertension, or kidney disease and is up to date with all recommended vaccinations. Physical examination is unremarkable. Blood type and crossmatch testing demonstrate biological compatibility. As part of the evaluation, screening for transmissible diseases is performed and is notable for the following results: Based on these data, the patient most likely has had which of the following conditions in the past?

Question

A 26-year-old man is being screened as a potential kidney donor for his mother, who has end-stage renal disease.  The patient has no history of diabetes, hypertension, or kidney disease and is up to date with all recommended vaccinations.  Physical examination is unremarkable.  Blood type and crossmatch testing demonstrate biological compatibility.  As part of the evaluation, screening for transmissible diseases is performed and is notable for the following results:  Based on these data, the patient most likely has had which of the following conditions in the past?

Quizplus · Accepted Answer

Eductional Objective: Cytomegalovirus (CMV) is typically associated with subclinical infection in the immunocompetent, with the occasional individual developing a mononucleosis-like syndrome that is heterophile antibody (Monospot) negative.  In the immunocompromised, primary or reactivated CMV infection can result in severe retinitis, pneumonia, esophagitis, colitis, or hepatitis.

A 26-Year-Old Man Is Being Screened as a Potential Kidney