A 28-year-old man comes to the physician because of a 2-day history of intermittent bloody urine. He has not had dysuria or abdominal pain. There has been no change in urine output or urinary frequency. He has also had a runny nose, dry cough, and a sore throat for the past 4 days. He has no history of serious illness and takes no medications. His temperature is 38.1°C (100.6°F), pulse is 70/min, respirations are 14/min, and blood pressure is 140/80 mm Hg. Cardiopulmonary and abdominal examinations show no abnormalities. There is flank tenderness to palpation bilaterally. Urinalysis results are as follows: A renal biopsy is performed Which of the following findings is most likely to be seen on microscopic evaluation?

Question

A 28-year-old man comes to the physician because of a 2-day history of intermittent bloody urine. He has not had dysuria or abdominal pain. There has been no change in urine output or urinary frequency. He has also had a runny nose, dry cough, and a sore throat for the past 4 days. He has no history of serious illness and takes no medications. His temperature is 38.1°C (100.6°F), pulse is 70/min, respirations are 14/min, and blood pressure is 140/80 mm Hg. Cardiopulmonary and abdominal examinations show no abnormalities. There is flank tenderness to palpation bilaterally. Urinalysis results are as follows:  A renal biopsy is performed   Which of the following findings is most likely to be seen on microscopic evaluation?

Quizplus · Accepted Answer

Eductional Objective: IgA nephropathy (Berger disease) frequently presents as recurrent, self-limited, painless hematuria; episodes often occur concurrently with an upper respiratory tract infection.  Kidney biopsy will show mesangial IgA deposits on immunofluorescence.  In contrast, poststreptococcal glomerulonephritis is seen 1-3 weeks after streptococcal pharyngitis and is usually not recurrent.

A 28-Year-Old Man Comes to the Physician Because of a 2-Day