A 26-year-old woman presented to the office complaining of a lump in her left breast. Her maternal aunt died from ovarian cancer at age 36 and her mother died from breast cancer at age 32. The patient is diagnosed with breast cancer following appropriate therapy. The gene affected is most likely responsible for which of the following?

Question

Quizplus · Accepted Answer

Eductional Objective: 
BRCA1 and BRCA2 mutations are most commonly associated with hereditary breast cancer. BRCA genes are involved in DNA repair, mutations in these genes increase the risk of breast and ovarian cancer.

A 26-Year-Old Woman Presented to the Office Complaining of a Lump