A 35-year-old man is brought to the emergency department after experiencing a seizure. According to his girlfriend, he has had fatigue for the last 3 days and became confused this morning, after which he started having uncontrollable convulsions throughout his entire body. He was unconscious throughout the episode, which lasted about 4 minutes. He has not visited a physician for over 10 years. He has smoked one pack of cigarettes daily for 12 years. Imaging of the brain shows a solitary mass within the temporal lobe. Biopsy of the mass reveals uniform cells containing the Epstein-Barr virus genome. This patient most likely suffers from which of the following?

Question

A 35-year-old man is brought to the emergency department after experiencing a seizure. According to his girlfriend, he has had fatigue for the last 3 days and became confused this morning, after which he started having uncontrollable convulsions throughout his entire body. He was unconscious throughout the episode, which lasted about 4 minutes. He has not visited a physician for over 10 years. He has smoked one pack of cigarettes daily for 12 years. Imaging of the brain shows a solitary mass within the temporal lobe.  Biopsy of the mass reveals uniform cells containing the Epstein-Barr virus genome.  This patient most likely suffers from which of the following?

Quizplus · Accepted Answer

Eductional Objective: Primary CNS lymphomas occur in immunosuppressed patients, such as those suffering from AIDS.  These tumors arise from B cells and are universally associated with EBV.  They are high-grade tumors with a poor prognosis.

A 35-Year-Old Man Is Brought to the Emergency Department After