A 60-year-old woman is brought to the hospital due to progressive dyspnea. In the emergency room, patient was found unresponsivenss and despite cardiopulmonary resuscitation, she died. A photograph of the lung as seen at autopsy is shown below. Which of the following underlying histopathological changes are most likely to be seen within this patient's lungs?

Question

A 60-year-old woman is brought to the hospital due to progressive dyspnea. In the emergency room, patient was found unresponsivenss and despite cardiopulmonary resuscitation, she died. A photograph of the lung as seen at autopsy is shown below.  Which of the following underlying histopathological changes are most likely to be seen within this patient's lungs?

Quizplus · Accepted Answer

Eductional Objective: Emphysema (ie, alveolar destruction and enlargement) develops from a combination of inflammation and leukocyte infiltration, increased protease activity, and oxidative stress, usually in response to cigarette smoke exposure.  In severe disease, large air spaces known as subpleural blebs can form in the lung apices.

A 60-Year-Old Woman Is Brought to the Hospital Due to Progressive