A 28-year-old nulliparous woman comes to the clinic for an infertility evaluation. The patient has had unprotected intercourse with her husband for the past 12 months without conceiving and often experiences pain with deep vaginal penetration. The patient also reports episodic pelvic and back pain accompanied by painful diarrhea for 5 years. She has about one such episode on average per month that lasts 4-6 days. The pain has persisted despite medical therapy and is suspected to be due to endometriosis. Exploratory laparoscopy is performed, and multiple flesh-colored nodules are present on the pelvic organs, along with thin, filmy adhesions. In addition to having endometrial glands with hemosiderin pigment, one of the biopsies contains simple cuboidal epithelial cells. Which of the following is the most likely site of the biopsy?

Question

A 28-year-old nulliparous woman comes to the clinic for an infertility evaluation.  The patient has had unprotected intercourse with her husband for the past 12 months without conceiving and often experiences pain with deep vaginal penetration. The patient also reports episodic pelvic and back pain accompanied by painful diarrhea for 5 years. She has about one such episode on average per month that lasts 4-6 days. The pain has persisted despite medical therapy and is suspected to be due to endometriosis.  Exploratory laparoscopy is performed, and multiple flesh-colored nodules are present on the pelvic organs, along with thin, filmy adhesions.  In addition to having endometrial glands with hemosiderin pigment, one of the biopsies contains simple cuboidal epithelial cells.  Which of the following is the most likely site of the biopsy?

Quizplus · Accepted Answer

Eductional Objective: The uterine mucosa is covered by endometrium, and abnormal implantation of endometrial glands/stroma is referred to as endometriosis.  The ovary is covered by a simple cuboidal epithelium involved in surface repair of defects from ovulation.  Endometriosis commonly affects the ovary and results in infertility.

A 28-Year-Old Nulliparous Woman Comes to the Clinic for an Infertility