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A 48-Year-Old Woman Visits the Office Because She Has Been

Question 473

Multiple Choice

A 48-year-old woman visits the office because she has been experiencing prolonged heavy monthly bleeding. The patient has monthly menstruation, which lasts 5-6 days and is accompanied by severe bleeding, the passage of big blood clots, and intensified stomach cramps. She has had two vaginal births and has no serious medical history. Her mother's endometrial cancer is an important family history. 24 kg/m2 is the BMI. The vital indicators are typical. Ultrasound of the pelvis reveals a uterine lump. A complete abdominal hysterectomy is performed on the patient; the gross examination of the uterus is displayed below: A 48-year-old woman visits the office because she has been experiencing prolonged heavy monthly bleeding. The patient has monthly menstruation, which lasts 5-6 days and is accompanied by severe bleeding, the passage of big blood clots, and intensified stomach cramps. She has had two vaginal births and has no serious medical history. Her mother's endometrial cancer is an important family history. 24 kg/m<sup>2</sup> is the BMI. The vital indicators are typical. Ultrasound of the pelvis reveals a uterine lump. A complete abdominal hysterectomy is performed on the patient; the gross examination of the uterus is displayed below:   The abnormal region indicated by the arrow is most likely to display which of the following microscopic findings? A) Dysplastic squamocolumnar cells with areas of atypia B) Ectopic endometrial glands and hemosiderin-laden macrophages C) Hyperplastic proliferation of irregular endometrial glands D) Infiltration of the stroma by high-grade serous carcinoma E) Monoclonal proliferation of myocytes and fibroblasts The abnormal region indicated by the arrow is most likely to display which of the following microscopic findings?


A) Dysplastic squamocolumnar cells with areas of atypia
B) Ectopic endometrial glands and hemosiderin-laden macrophages
C) Hyperplastic proliferation of irregular endometrial glands
D) Infiltration of the stroma by high-grade serous carcinoma
E) Monoclonal proliferation of myocytes and fibroblasts

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