A 34-year-old guy arrives to the clinic with a lingering skin rash. He has a 6-month history of a scaly rash on his upper and lower limbs, which is accompanied by moderate pruritus. The patient has tried topical antihistamines and emollients without success. Childhood asthma and orolabial herpes simplex virus infection stand out in the patient's medical history. He does not smoke or drink and works as a sales associate for a home improvement business. The patient was found to have skin lesions, as indicated in the photograph below. On histology, psoriasis is distinguished by hyperkeratosis and confluent parakeratosis of the stratum corneum (which results in the typical silvery scales visible on visual examination), as well as widespread epidermal hyperplasia with elongated and clubbed rete ridges. This patient's disorder is most likely associated with which of the following extradermal complications?

Question

A 34-year-old guy arrives to the clinic with a lingering skin rash. He has a 6-month history of a scaly rash on his upper and lower limbs, which is accompanied by moderate pruritus. The patient has tried topical antihistamines and emollients without success. Childhood asthma and orolabial herpes simplex virus infection stand out in the patient's medical history. He does not smoke or drink and works as a sales associate for a home improvement business. The patient was found to have skin lesions, as indicated in the photograph below. On histology, psoriasis is distinguished by hyperkeratosis and confluent parakeratosis of the stratum corneum (which results in the typical silvery scales visible on visual examination), as well as widespread epidermal hyperplasia with elongated and clubbed rete ridges.  This patient's disorder is most likely associated with which of the following extradermal complications?

Quizplus · Accepted Answer

Eductional Objective: This patient has psoriasis, as evidenced by well-demarcated, scaly, erythematous plaques on the extensor surfaces of the extremities. Psoriasis patients frequently acquire extra problems, such as:
Psoriatic arthritis is an inflammatory condition that affects the synovium and, in certain cases, the insertion of tendons and ligaments (ie, enthesopathy). It usually manifests as asymmetric oligoarthritis or symmetric polyarthritis (similar to rheumatoid arthritis) affecting the distal interphalangeal joints. Patients with severe instances may develop an aggressive and destructive arthritis mutilans. Patients who test positive for human leukocyte antigen B27 are at a higher risk.

A 34-Year-Old Guy Arrives to the Clinic with a Lingering