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A 34-Year-Old Man Comes to the Physician Because of Increasing

Question 656

Multiple Choice

A 34-year-old man comes to the physician because of increasing lower back and neck pain for the past 7 months. The pain is worse in the morning and improves when he plays basketball. He has noticed shortness of breath while playing for the past 2 months. He is sexually active with two female partners and uses condoms inconsistently. He appears lethargic. His vital signs are within normal limits. Examination of the back shows tenderness over the sacroiliac joints. Range of motion is limited by pain. The lungs are clear to auscultation. Chest expansion is decreased on full inspiration. Erythrocyte sedimentation rate is 75 mm/hr.  Which of the following pathologic findings is most likely causing this patient's symptoms?


A) Areas of bony erosions and new bone formation
B) Areas of spindle cells and dysplastic bone
C) Areas of trabecular and cortical bone thickening
D) Disc protrusion and thickening of the ligamentum flava
E) Plasma cell infiltrate in bone marrow

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