According to research, synaptic transmission is potentiated as a result of repeated stimulation of hippocampus neurons involved in memory and learning. Below are patch-clamp recordings of activated neurons. (dotted line: baseline; solid line: after repeated stimulation [potentiated]). Which of the following neurotransmitter receptors on the postsynaptic membrane is most likely involved in this process?

Question

According to research, synaptic transmission is potentiated as a result of repeated stimulation of hippocampus neurons involved in memory and learning. Below are patch-clamp recordings of activated neurons. (dotted line: baseline; solid line: after repeated stimulation [potentiated]).  Which of the following neurotransmitter receptors on the postsynaptic membrane is most likely involved in this process?

Quizplus · Accepted Answer

Eductional Objective: The primary excitatory neurotransmitter of the CNS, glutamate, causes calcium entry through the NMDA receptor and postsynaptic cell depolarization. The molecular basis for memory, learning, and addiction is long-term potentiation, which is calcium entry programming the neuron to undergo more robust depolarization in response to repeated stimulation.

According to Research, Synaptic Transmission Is Potentiated as a Result