A 70-year-old man is found died in his house this morning. He was living alone after his wife passed away last year. postmartem biopsy revealed the cause of death is due to pulmonary embolism. the biopsy also demonstrates decreased left ventricular cavity size and a sigmoid-shaped ventricular septum. Light microscopy shows increased collagen content within the ventricular wall. Some myocardial cells also have brownish perinuclear cytoplasmic inclusions. The changes described are most consistent with which of the following conditions?

Question

A 70-year-old man is found died in his house this morning. He was living alone after his wife passed away last year. postmartem biopsy revealed the cause of death is due to pulmonary embolism. the biopsy also demonstrates decreased left ventricular cavity size and a sigmoid-shaped ventricular septum.  Light microscopy shows increased collagen content within the ventricular wall.  Some myocardial cells also have brownish perinuclear cytoplasmic inclusions.  The changes described are most consistent with which of the following conditions?

Quizplus · Accepted Answer

Eductional Objective: Normal morphological changes in the aging heart include a decrease in left ventricular chamber apex-to-base dimension, development of a sigmoid-shaped ventricular septum, myocardial atrophy with increased collagen deposition, and accumulation of cytoplasmic lipofuscin pigment within cardiomyocytes.

A 70-Year-Old Man Is Found Died in His House This