A 23-year-old man arrives at the clinic with a painful, growing lesion on his chest. Six months ago, the patient suffered a laceration injury to the chest. On examination, the image below shows a pink, firm plaque.
Which of the following is most likely responsible for this patient's lesion?
A) Decreased insulin-like growth factor-1 signaling
B) Decreased PDGF receptor activation on fibroblasts
C) Increased fibroblast apoptosis rate
D) Overexpression of transforming growth factor beta
E) Overproduction of matrix metalloproteinases
Correct Answer:
Verified
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