A healthy 32-year-old man enrolls in a clinical study investigating potassium handling by the kidney. During the study period, he is given oral potassium supplements and potassium levels in the serum and urine are closely monitored. Compared to the amount of potassium delivered to the glomerular capillaries, the percentage of potassium remaining in this individual's tubular fluid is most likely to vary by which of the following amounts?

Question

A healthy 32-year-old man enrolls in a clinical study investigating potassium handling by the kidney.  During the study period, he is given oral potassium supplements and potassium levels in the serum and urine are closely monitored.  Compared to the amount of potassium delivered to the glomerular capillaries, the percentage of potassium remaining in this individual's tubular fluid is most likely to vary by which of the following amounts?

Quizplus · Accepted Answer

Eductional Objective: Pottasium is freely filtered by the glomeruli and is mostly reabsorbed in the proximal tubule and loop of Henle. As such, the late distal and cortical collecting tubules are the primary sites for regulation of Pottasium excretion in the urine. Pottasium depletion stimulates alpha-intercalated cells to reabsorb extra potassium principal cells secrete Pottasium under conditions of increased Pottasium load.

A Healthy 32-Year-Old Man Enrolls in a Clinical Study Investigating