A newborn by normal vaginal delivery is brought for routine screening. you found an increase in TSH and low thyroxine T4 serum level. Apgar scores were 8 and 9 at 1 and 5 minutes, respectively. His mother has no medical conditions. Physical examination reveals normal thyroid gland in the normal position. Neck ultrasound confirms the normal size of the thyroid. Which of the following is the most likely cause of this patient's findings?

Question

Quizplus · Accepted Answer

Eductional Objective: Congenital hypothyroidism has multiple causes one of them is a mutation in the TSH receptors gene which leads to TSH resistance. It is characterized by normal size of thyroid gland with an increase in TSH and low thyroxine.

A Newborn by Normal Vaginal Delivery Is Brought for Routine