A 30-year-old male patient is in the emergency room because he was belligerent, confused, and delirious. His girlfriend called the police because of this behavior, and she said it started after smoking marijuana. Suspicions are that the marijuana was altered with phencyclidine (PCP). Which receptors are mainly altered by PCP?
A) N-methyl-D-aspartate (NMDA)
B) Serotonin receptors
C) Monoamine receptors
D) Dopamine receptors

Question

Quizplus · Accepted Answer

PCP primarily acts as an antagonist at the N-methyl-D-aspartate (NMDA) receptors, which are a subtype of glutamate receptors in the brain. This action is responsible for its dissociative and hallucinogenic effects.

A 30-Year-Old Male Patient Is in the Emergency Room Because