The cause of a decreased glomerular filtration rate in rapidly progressive glomerulonephritis is due to the development of:
A) podocyte proliferation.
B) small vessel thrombosis.
C) albumin that gets trapped in the loop of Henle.
D) collagen and fibrin deposits that develop into crescents.

Question

Quizplus · Accepted Answer

In rapidly progressive glomerulonephritis, the decreased glomerular filtration rate is primarily due to the formation of crescents, which are composed of collagen and fibrin deposits in Bowman's space, leading to compression and dysfunction of the glomeruli.

The Cause of a Decreased Glomerular Filtration Rate in Rapidly