Surrogate endpoints for a clinical trial of a drug to control hypertension may include:
A) subclinical disease.
B) physical measures such as reduction in blood pressure.
C) occurrence of strokes and heart attacks.
D) subclinical disease and physical measures such as reduction in blood pressure.

Question

Quizplus · Accepted Answer

Surrogate endpoints are used to predict the clinical outcome of a treatment. In the case of hypertension, surrogate endpoints may include subclinical disease (e.g., increased arterial stiffness) and physical measures such as reduction in blood pressure.

Surrogate Endpoints for a Clinical Trial of a Drug to Control