A physician receives a cut from a bloody scalpel while operating on an HIV-infected woman and initiates three-drug PEP immediately following the exposure. The soonest it can be documented that no transmission from the exposure occurred is:
A) 4 weeks following exposure, by a HIV RNA assay
B) 6 weeks following exposure, by a negative fourth-generation antigen-antibody test
C) 4 months following the exposure, with a negative fourth-generation antigen-antibody test
D) 6 months following the exposure, with a negative HIV antibody test

Question

Quizplus · Accepted Answer

PEP is highly effective in preventing HIV transmission after exposure, and a negative fourth-generation antigen-antibody test at 4 months following exposure is considered definitive evidence of no transmission.

A Physician Receives a Cut from a Bloody Scalpel While