You Are the Primary Care Provider for a 55-Year-Old Male

You are the primary care provider for a 55-year-old male who is currently on preexposure prophylaxis (PrEP) and reports 100% daily adherence for the past 6 months. He comes into clinic stating that last night he had unprotected receptive anal intercourse with an HIV-infected male who is not adherent to his ARV therapy. Your priority is to:

A) Offer the patient three-drug PEP for this high-risk exposure
B) Obtain the resistance profile of the patient's partner
C) Reassure the patient that PrEP, when taken daily, provides a 92% to 99% reduction in HIV risk and continue with routine surveillance
D) Reassure the patient that transmission is likely but that he should stop PrEP today to reduce the chance of creating resistant virus