A Patient Reports She Is Having Symptoms of Hypoglycemia at 11am

A patient reports she is having symptoms of hypoglycemia at 11am at least three times a week. She reports skipping breakfast and taking her glipizide 10 mg at 7am with water. She also takes metformin 1,000 mg twice daily and glargine 23 units at bedtime. Patient weighs 90 kg and has had diabetes for 10 years. You explain that:

A) Her symptoms of hypoglycemia are likely due to her glargine and taking metformin at the same time.
B) Her symptoms of hypoglycemia are likely due to her lack of food intake in the morning (breakfast) and the timing of her glipizide.
C) Her hypoglycemia is not related to her medication regimen or eating patterns.
D) Her hypoglycemia is likely to due to high-dose metformin and her lack of food.