An in vivo model should have all the biochemical,cellular,and physiological complexities of human systems to successfully predict the actual efficacy of the drug candidate.
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Q1: The setting of druggability and developability criteria
Q2: Drug absorption is often limited by the
Q3: A drug needs to be commercially viable
Q4: In the initial stages of drug discovery,new
Q6: Bioavailability is an important pharmacodynamics parameter.
Q7: Total body clearance is the rate at
Q8: The crystalline state,salt form,and the presence of
Q9: For most drugs (unless they are rapidly
Q10: Toxicological studies for a new molecule are
Q11: As long as the active drug is
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