While there are restrictions for compounds to gain access to brain,there are mechanisms that can be exploited to facilitate brain penetration,which include:
A) efflux transporters
B) influx transporters
C) receptor mediated transporters
D) enzymatic proteins
E) A & B
F) A & C
G) A & D
H) B & C
I) B & D
J) C & D
Correct Answer:
Verified
Q2: A fatty material called _ coats nerve
Q3: The _ restricts the passive diffusion of
Q4: The brain capillaries generally have _.
A) high
Q5: Factors limiting drug penetration into the brain
Q6: Occludin,claudins and intercellular junctional adhesion molecules are
Q8: _ is a common measure of lipophilicity
Q9: Lipinski "Rule of Five" aims to correlate
Q10: According to Lipinski's "Rule of Five",the number
Q11: According to Lipinski's "Rule of Five",the number
Q12: For successful CNS therapy,the Active Pharmaceutical Ingredient
Unlock this Answer For Free Now!
View this answer and more for free by performing one of the following actions
Scan the QR code to install the App and get 2 free unlocks
Unlock quizzes for free by uploading documents