Peptide and protein drug delivery by the nasal route is complicated by disease state mostly due to higher mucus levels leading to increased residence time and half-life.

Question

Quizplus · Accepted Answer

Higher mucus levels in disease states can actually decrease the residence time and half-life of peptide and protein drugs delivered nasally, as the mucus can act as a barrier to absorption.

Peptide and Protein Drug Delivery by the Nasal Route Is