A permanent, abnormal dilatation of one or more large bronchi as a result of destruction of the elastic and muscular components of the bronchial wall best describes

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Bronchiectasis is a condition where there is permanent dilation of one or more bronchi, typically caused by inflammation or infection that damages the elastic and muscular components of the bronchial wall. COPD and emphysema are broader terms that refer to a group of lung diseases that cause difficulty breathing, but they do not necessarily involve bronchial dilation. Pleurisy is an inflammation of the lining of the lungs and chest cavity and does not involve bronchial dilation.

A Permanent, Abnormal Dilatation of One or More Large Bronchi