A category 2 risk of colon cancer is defined as a high risk; it includes hereditary syndromes such as hereditary nonpolyposis colorectal cancer (HNPCC)and familial polyposis, or patients with a personal history of ulcerative colitis or Crohn disease.

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A category 2 risk of colon cancer is considered moderate risk, not high risk. High risk typically refers to category 3, which includes hereditary syndromes like hereditary nonpolyposis colorectal cancer (HNPCC) and familial adenomatous polyposis. Category 2 often includes individuals with a strong family history of colon cancer but not necessarily those with hereditary syndromes or a personal history of significant inflammatory bowel disease.

A Category 2 Risk of Colon Cancer Is Defined as a High