A patient states that he has been taking Demerol 50 mg tablets four times a day for the past 5 years, but they are not working like they use to.The nurse is concerned that the patient has developed

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Addiction is defined by a pattern of compulsive drug use that is characterized by an incessant longing for an opioid and the need to use it for effects other than pain relief.Tolerance is defined as a diminution of opioid effects over time.Physical dependence and tolerance to opioids may develop if the medication is given over a long period.Physical dependence is manifested by withdrawal symptoms when the opioid is abruptly stopped.

A Patient States That He Has Been Taking Demerol 50