A 6-year-old female presents to your pediatrics office with facial tenderness, cough, purulent rhinorrhea, and fever. A brief review of her history reveals frequent antibiotic use for recurrent lung infections. You recommend biochemical analysis to examine for an enzymatic defect in chloride and water transport, also known as:

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Biochemical analysis is used for the detection of cystic fibrosis because it is used to detect the presence of proteins, namely enzymes. Answer A is incorrect because phenylketonuria (PKU) is an absence or deficit in phenylalanine hydroxylase, which catabolizes phenylalanine. Answer B is incorrect because primary ciliary dyskinesia is a congenital condition where mucus clearance is impaired due to defective or absent cilia. Answer C is incorrect because primary immunodeficiency is a susceptibility to diseases due to poor antibody production. Thus, answer D is the correct choice.

A 6-Year-Old Female Presents to Your Pediatrics Office with Facial