It is likely that the chimeric fusion proteins resulting from reciprocal translocations act as transcription activators that deregulate key genes associated with pediatric sarcoma development.
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Q2: About 30% of bone sarcomas are diagnosed
Q3: The death curve for bone sarcomas shows
Q4: The incidence of soft tissue sarcomas is
Q5: The death curve for soft tissue sarcoma
Q6: Reciprocal chromosomal translocations constitute the majority of
Q8: Chimeric fusion proteins resulting from reciprocal translocations
Q9: Adult sarcomas are often characterized by reciprocal
Q10: Lipomas are benign tumors that develop from
Q11: Uterine fibroids are benign tumors that develop
Q12: Lipomas and uterine fibroids often undergo malignant
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