If a drug that blocks Na-K-2Cl cotransporters is administered, blood pressure will _______ and plasma sodium concentration will _______.

Question

Quizplus · Accepted Answer

Blocking Na-K-2Cl cotransporters, such as with loop diuretics, leads to decreased reabsorption of sodium, potassium, and chloride in the kidneys. This results in increased urine output, decreased blood volume, and consequently decreased blood pressure. The loss of sodium in the urine can also lead to a decrease in plasma sodium concentration.

If a Drug That Blocks Na-K-2Cl Cotransporters Is Administered, Blood