A 43-year-old female presents to the emergency department with encephalopathy. She has been undergoing chemotherapy for the past 3 months for treatment of ovarian cancer. ALT 170 units/L and AST 120 units/L. Ammonia level is 250, and her mental status is obtunded. Her husband reports that she drinks a glass of wine every night. What is the culprit of her acute liver failure?

Question

Quizplus · Accepted Answer

Chemotherapy is the most likely cause of acute liver failure in this patient, as it can be hepatotoxic and lead to elevated liver enzymes and encephalopathy.

A 43-Year-Old Female Presents to the Emergency Department with Encephalopathy