Pain-Induced Release of Substance P in the Dorsal Horns of the Spinal

Pain-induced release of substance P in the dorsal horns of the spinal cord causes

A) remodeling of presynaptic axons, perhaps blocking subsequent pain signals.
B) remodeling of dendrites, perhaps altering later pain perception.
C) increased production of acetylcholine receptors, which improves pain suppression by the brain.
D) reduction of endogenous opiate secretion, which allows important pain stimuli to reach the brain.