How does kainic acid cause toxicity to mammalian neuronal cells? What common local anesthetic agent do something opposite?

Name: How does kainic acid cause toxicity to mammalian neuronal cells? What common local anesthetic agent do something opposite?
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Question

Quizplus · Accepted Answer

The Answer is Kainic acid targets glutamate receptors increasing Na⁺ movement into these cells (overstimulates). Lidocaine blocks Na⁺ channels and would have opposite effects at concentrations that were anesthetic.

How Does Kainic Acid Cause Toxicity to Mammalian Neuronal Cells